I know I year has past and I hope you have some further answers. I am an active 58-year-old recently diagnosed with osteoporosis. (I had to push for a DEXA scan since I measured 2" less than I had since I was 14.) I too have high PTH indicator (108). My calcium levels are within normal limits as well as my vitamin D, but my vitamin D is on the lower end (31). I was put on Fosamax (a weekly Bisphosphonate) and was suggested to do Reclast.
I questioned doing the Reclast because of my high PTH and if it was determined I needed a different treatment option, I would have to wait to do so for a full year. They don't plan to retest my PTH for 6 months. My T-scores are -3.6 Lumbar Spine, -2.0 Right Femoral Neck, and -2.1 Total Right Proximal Femur/Hip.
In doing some research about my options, I ran across this doctor peer to peer discussion/training on standard protocol for osteoporosis - antiresorptive followed by anabolic. The studies showed that doing the anabolic agent first followed by antiresorptive yielded greater BMD and that the antiresorptive followed by anabolic blunted the BMD response. Don't we all want more BMD if we have osteoporosis!! I was told, however, I can't do the anabolic because my PTH is high. I too am researching and looking for a second opinion to determine if that truly is the case. Since the Parathyroid plays such a key roll in all of this, I want to have my questions answered.
Here is the link to the discussion if you are interested Google this: Combined and Sequential Approaches to Osteoporosis Therapy, source Cleveland Clinic
In addition, here are some additional sites I have found but haven't fully read them, just skimmed to see if they might yield some insight.
Endogenous intact PTH is suppressed during Teriparatide (rhPTH 1-34) administration in postmenopausal women with established osteoporosis - PubMed
Chronic hypoparathyroidism and treatment with teriparatide - PMC
Teriparatide in postmenopausal osteoporosis: uncovering novel insights into efficacy and safety compared to other treatments – a systematic review and meta-analysis - PMC
As new member, I can't post the links, but you should be able to get there as those are the names of the studies.
I hope this helps.
@jenniferinva2025, I noticed that you wished to post a URL to an article with your post. You will be able to add URLs to your posts in a few days. There is a brief period where new members can't post links. We do this to deter spammers and keep the community safe. Clearly the link you wanted to post is not spam. Please allow me to post it for you.
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"Endogenous intact PTH is suppressed during Teriparatide (rhPTH 1-34) administration in postmenopausal women with established osteoporosis"
- https://pubmed.ncbi.nlm.nih.gov/18520104/
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"Chronic hypoparathyroidism and treatment with teriparatide"
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8087564/#Sec7
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"Teriparatide in postmenopausal osteoporosis: uncovering novel insights into efficacy and safety compared to other treatments – a systematic review and meta-analysis"
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11457814/