I've had the diagnosis of Collagenous colitis for some months. I've been on Budesonide -- but kept having UTIs and antibiotics, so eventually the budesonide didn't work. Somewhere in that time, i was told to stop methotrexate, so it's interesting to hear that methotrexate helped someone! I'm now in limbo, with a Dec. appointment with Mayo, and an appointment with my PCP Tuesday Nov 3, so that will be a fraught day in a couple of ways! My digestive health people seem out of their depth. They handed me the FODMAP diet but without many instructions, so I've been following it but the diarrhea persists. Googling shows some evidence that FODMAP is not the diet doctors recommend for collagenous colitis, since it was developed for IBS. In any case, I'm finding this confusing, and am eager to hear more expert advice. Meanwhile, I do think that diet may be the best way to control my colitis -- but don't think I've been getting a good education on what that diet should be. Whew! This has been almost a year for me -- and I'm feeling depleted and worn out by trying to get through this.