I was diagnosed with IBS 20 years ago, after having a normal digestive system. I have chronic UTIs, which resulted in 10 years of chronic CDIFF. I have had this distension, puffy, painful for a year. I cannot wait to go back to Mayo Clinic , hopefully to find out if they can do anything for distension. I also had toxic mega colon and in Dec. Sepsis. I have hope in Mayo Clinic...It's been a tough go.