I will tell that you have to give HRT a long time to settle in. It probably took me a year at least to find the best stable regimen for me, and it will differ for everyone what level of hormones you feel best at. It also differs what you need if you have a uterus/still bleed or not. I've endured a lot of side effects from the hormones, but the effects of menopause were so awful on me it was worth it. I have not had gains or stability of my osteoporosis in the spine unfortunately. I was really hoping it would work. I want to use one of the bone building drugs because my density is so low...I've tried Evenity and Tymlos so far. Had awful insomnia for a full month on Evenity...i literally could barely sleep for a month, and it also gave me tooth pain. On the full dose of Tymlos I had horrible migraines and just a really sick flu feeling. I'm trying it at a lower dose now, but am not sure that will work or give me the same improvement. I've had awful gut problems from the anti resorptive drugs, and will not risk more fractures from these meds.

@sondrachristo1 I am having similar reactions to you. I first tried risedronate with terrible pain in my arms and legs. Then in Feb 2026 I was given Prolia. I am totally crippled. I feel like I am walking on rocks. My hands are so sore I can hardly use them. My wrists ache. Two weeks ago my knee gave out with acute pain. I am 69 years old with a -3.5 SD for osteoporosis. My back aches if I stand up too long. I will not take the next shot in August. I don't want to live like this. I am also dealing with the thought of having a shortened life because of this drug but I would rather live a few more years without pain than try any of these drugs again.