I will tell that you have to give HRT a long time to settle in. It probably took me a year at least to find the best stable regimen for me, and it will differ for everyone what level of hormones you feel best at. It also differs what you need if you have a uterus/still bleed or not. I've endured a lot of side effects from the hormones, but the effects of menopause were so awful on me it was worth it. I have not had gains or stability of my osteoporosis in the spine unfortunately. I was really hoping it would work. I want to use one of the bone building drugs because my density is so low...I've tried Evenity and Tymlos so far. Had awful insomnia for a full month on Evenity...i literally could barely sleep for a month, and it also gave me tooth pain. On the full dose of Tymlos I had horrible migraines and just a really sick flu feeling. I'm trying it at a lower dose now, but am not sure that will work or give me the same improvement. I've had awful gut problems from the anti resorptive drugs, and will not risk more fractures from these meds.