I went to emergency in November 2023 and did the biopsy in December. And then was diagnosed with CUP in December 2023. Although they tried ultrasound, MRI and PET scan after, no primary can be found still and they told me no pint to find that. I did the chemo and immunotherapy right away. After 16 chemos, I was on immunotherapy for around 6 months. Now they asked me to start new chemo again because the lymph nodes are getting bigger again. The swollen lymph nodes are several areas. This is very frustrating since no targeted medicine could be taken and stage 4 is not curable too. I would like to hear more suggestions if you know of anybody having similar situations.