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‘Big Guns’ - Triple Therapy with Double Chemo - How to prepare?

Prostate Cancer | Last Active: Apr 16 11:29am | Replies (13)
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@dpfbanks

Thanks, @jeffmarc. I have been a fan of SRBT from reading papers, but our team isn’t a fan of SBRT above the diaphragm unless it a solitary nodule… we had hope for some directed therapy and even wondered about Lutetium, but I guess the game is to save some tools in the toolbox for later. And we asked about Orgovyx and the response was ‘ we haven't used it in triple therapy before’ - it wasn’t a no, but it wasn’t a yes. We will finalize with our oncologist next week. Thanks for responding - it’s scary to be starting with so many things when he hasn’t even done ADT or radiation of any kind.

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Replies to "Thanks, @jeffmarc. I have been a fan of SRBT from reading papers, but our team isn’t..."
northoftheborder | @northoftheborder | Apr 15 5:49pm

My chart says I got 20 gy of post-op SBRT to my middle spine (T3, well above the diaphragm) in 2021, after the surgery to debulk the lesion. It's very important that you stay perfectly still when they're working near so many vital organs. For me, they made a custom cage that held my head immobilised during radiation.

It was very uncomfortable, but on the bright side, I'm not aware of any side-effects from that round of radiation therapy.

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northoftheborder | @northoftheborder | Apr 15 5:56pm

Orgovyx is basically the same thing as Firmagon — a GnRH antagonist — but in pill form (at least that's what my oncologist told me), so if they're comfortable with Firmagon injections, Orgovyx shouldn't be a big departure for them, and in my experience it significantly cut down on the discomfort of ADT (vs injections).

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