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Erdosteine for Bronchiecstasis

MAC & Bronchiectasis | Last Active: May 10 7:45am | Replies (2)
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@scoop

Sorry to hear about your pneumonia! It's quite sneaky.

Eddosteine looks to be a cousin of NAC but not as long lasting or as potent. Here's a study describing its effectiveness in COPD, European based. Not a panacea for bronchiectasis but another something that might give some relief.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5678897/

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Replies to "Sorry to hear about your pneumonia! It's quite sneaky. Eddosteine looks to be a cousin of..."
bsi15 | @bsi15 | May 10 7:45am

Zatloukal J, Page C, Brat K et al (2025) Effect of treatment
with mucoactive drugs on chonic obstructive pulmonary dis-
ease exacerbations during 5 years of follow-up in the Czech
Republic: a real-world study. Lung. https:// doi. org/ 10. 1007/
s00408- 025- 00813-7
In summary, the Zatloukal et al. study helps fill the gap in
the algorithm for preventing exacerbations of COPD with a
broadly available and inexpensive drug without safety sig-
nals. Importantly, the effect size of this treatment is like
other add-on treatments, i.e., inhaled corticosteroids, bron-
chodilators, biologics, or rehabilitation for the prevention of
COPD exacerbations.

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