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DiscussionStarting pre-tests for CAR-T infusion for multiple myeloma
Bone Marrow Transplant (BMT) & CAR-T Cell Therapy | Last Active: 3 days ago | Replies (15)Comment receiving replies
Replies to "No journal. My neutrophils and platelets took a real dip. I guess this is not unusual..."
It’s very normal for neutrophils, platelets and red blood counts to drop quite low during this period. It is called nadir or neutropenia, which is the side-effect of the preconditioning chemo.
In the process of clearing your bone marrow of any cancer cells, the chemo doesn’t discriminate. So other quickly dividing cells may be impacted such as blood cells, hair follicles, mucosal tissue in the mouth and digestive system. However, once your newly infused cells engraft, you’ll start seeing neutorphil counts rising again. From my experience and tales from others, engraftment seems to happen not long after you feel that extreme tiredness and lethargy. Then, boom, like magic those numbers start climbing and you start feeling much better.
It’s so cool when those new cells are infusioned…they flow through the blood stream and magically find these specilialized pores that allow them to enter the bone marrow! Once inside, they begin to set up housekeeping again, churning out new blood products! It’s a fascinating process. So hang in there, I would think you’re getting close!
Are you feeling up to walking around daily?