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Gleason score 3+4 plus perineural invasion
Prostate Cancer | Last Active: 56 seconds ago | Replies (17)Comment receiving replies
Perennial invasion is not a problem as long as you have the prostate treated.
You should be getting a PSMA pet test to see if the cancer has spread outside the prostate. This also gives you a benchmark against which future test can be compared.
According to a doctor at the latest PCRI conference “PNI and extra capillary extensions do not predict metastasis”
Have you had hereditary genetic testing? With your father getting the cancer so young, a genetic issue is possible and necessary. if any other relatives have had cancer in your family, that is also important to know I know at least three families where all the men got prostate cancer, but there was no “known”genetic reason. Has it been offered to you by a doctor? You can get it done free with the below link, if you live in the United States. Do not check the box that you want your doctor involved or they won’t send you the kit until they get in contact with your doctor. It takes about three weeks to get the results and then a genetic counselor will call you.
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Prostatecancerpromise.org
Replies to "Perennial invasion is not a problem as long as you have the prostate treated. You should..."
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Thanks for sharing that study website - I'll sign up.
The report noted nerve invasion (called perineural). The literature seems to be unclear about how common this is with some rates in the teens and others reported to be upwards of 70% of cases. There are a lot of nerves in and around the prostate. There also seems to be disagreement about how nerve invasion could impact spread in the prostate In other cancers, it's a common avenue of spread as the cancer cells readily travel along the nerves spreading to other body parts. This leads to disagreement on how important nerve invasion is for making treatment decisions in prostate cancer. Some say no big deal and others say it is. Seems like an area that needs more research. I'm interested to see what my doctor says when I have the first follow up after the biopsy report.