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DiscussionAnyone been prescribed Ohtuvayre (new med)? Your experience?
COPD: Chronic obstructive pulmonary disease | Last Active: 12 hours ago | Replies (143)Comment receiving replies
Replies to "I go see doc on Tuesday and discuss Breztri or other option. Thanks. I saw a..."
What did you dr say about Breztri? That’s what I’m on
Thanks
Well that link didn't work. Here is a snip:
RESULTS: Mean age was 64.3 years, with 52.2% under 65 years of age. Patients were primarily female (57.5%), caucasian (90.1%) and current smokers (55.3%) with chronic bronchitis (59%). Day 1 baseline IC was similar between treatment groups. Placebo-corrected change from baseline in IC on Day 1 (2h post-dose) was 76, 62, 115 and 108 mL for the 0.375, 0.75, 1.5, 3.0 mg ensifentrine + tiotropium groups, respectively. The 1.5 and 3 mg doses showed statistically significant improvements (p< 0.01). After 4 weeks of twice-daily ensifentrine added to once daily tiotropium, there was a statistically significant improvement of 110.2 mL in IC (2 h post-dose) compared with placebo (tiotropium alone, p=0.0290) with the 3 mg ensifentrine dose + tiotropium treatment group.
CONCLUSIONS: This study demonstrates a clinically meaningful response in IC after treatment with 4 weeks of ensifentrine in COPD patients who remain symptomatic and with impaired lung function despite the use of tiotropium.