Thanks Stella.,I lost my femur and knee and 3/4 quadriceps to surgery 20 months ago. Although the margins were clear 3 months later PET revealed it had metastasised. Probably before the surgery. I have the IDH1 gene mutation and I went into the clinical trial available for that but it was not successful. I now have multiple inoperable tumours in my limbs hips and pelvis. I do believe that earlier detection and surgery would have been my best hope. But I was misdiagnosed. I wish you well. Richard