Yes. I started with Lupron but got bad tachycardia episodes, suicidal thoughts, and severe depression. Plus, the nurse hit a nerve during one of my monthly injections and I couldn't walk for 20 minutes and was sore for two weeks. I switched to Orgovyx for my last three months and it was a bit better.

What's really got me worried, though, is I'm almost six months past my last Orgovyx pill. At three months my testosterone had recovered into low-normal range, I was feeling good, and Mr. Happy was working great. But at six months it had plummeted, along with estradiol. When I brought it up to the oncology nurse practitioner I was told "you had cancer so there's a price to pay." I don't want to accept that so am going to see an endocrinologist and a sexual health specialist so we'll see.