Connect
← Return to When is forteo prescribed and when is evenity prescribed?
Discussion
When is forteo prescribed and when is evenity prescribed?
Osteoporosis & Bone Health | Last Active: 3 days ago | Replies (19)Comment receiving replies
From what I understand, the gains with Forteo are rapid and then drop off significantly after the first year or maybe even at the latter end of the first year for some. Since PTH can have a catabolic effect on bone density, this short burst of hormone is "trickery" that the body eventually figures out, thus diminishing the bone building effect of the initial use. In my case, I went from -3.2 to -2.8 the first year and then to -2.9 the second, so I actually slightly lost density the second year. I think bone markers are crucial, from baseline and every few months to make sure the drug is still working in your favor.
Replies to "From what I understand, the gains with Forteo are rapid and then drop off significantly after..."
Connect
oh, Teb. I think you have later information than I have. https://pmc.ncbi.nlm.nih.gov/articles/PMC4947115/#:~:text=Summary%20In%20patients%20with%20osteoporosis,outcomes%20than%20shorter%20time%20periods.
Of course your own experience trumps anything written in these studies.
I would be interested in your bone markers throughout, if you have them handy and are willing.
I had a slow rise in bone markers in the first year and no real change in bmd, but a little change in fracture risk. The second year gave me real changes in P1NP plus changing my lowest reading from -3.3 to -2.6. If the bone markers are any measure this next dxa will show even more improvement.
The burst of hormone is a daily trick. The rise of P1NP instigates the rise of CTX which eventually exceeds the advantage of P1NP.
Were you able to get bone markers ordered every few months. The endocrinologist I see gave me a standing order for every three months. And I depend upon Jason Health for the rest. It is good to hear your results.