Using bone builders only
Has anyone only taken tymlos or forteo and not followed up with an anti resorptive? I cannot tolerate any of that class of drug. I wondered if it's just a given you lose the bone you gain on the former, or that is not always the case. Or has anyone found being on HRT helped to sustain bone increases?
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Mayblin had a great answer to medication options to follow up PTH. Thank you. The impostant thing is that you follow up with something and moniter its efficacy.
CTX is a bone marker for bone resorption/removal. CTX used in many ways, but particulatiy in monritering therapy effectiveness. YOu must follow proceedures to do the test or the results will not be meaningful.
( No biotin, collagen, bone broth 48 hours before/ early morning fasting draw 6-7am)
I see; this makes sense @dmshope, thanks for sharing. Hope that you have a great success with Evenity! Fingers crossed.
CTX is a test of the activity of your Osteoclasts, which are bone cells. Osteoclasts chew up old bone, and Osteoblasts are new bone builders. Osteoblasts are commonly tested with a P1NP. Both are blood tests. Few physicians seem interested in these bone marker tests, in my personal experience, and if you do convince them to run the tests, they do not know how to interpret them. But really, no one should be taking ANY bone drug without knowing and monitoring those numbers, before, after and during taking the drug. All this is my own humble opinion.
The study I read was done with teriparatide (Forteo). People in the study were followed-up up to 2 years after teriparatide cessation. Unlike Prolia which could lead to rapid loss of bmd gained during treatment and sometimes dropping below pre-treatment levels (which could result in multiple VCFs) after cessation without a follow-up drug, there were no "rebound" phenomenon with teriparatide in the study. I'd imagine bone loss afterwards resume the rate at pre-treatment.
Raloxifene is not a hormone itself but it mimics estrogen's effects in some tissues such as bones while blocks estrogen's effects in breast and uterus tissues. It's a good choice for someone who is considering HRT but has breast/uterus cancer risks. I read that raloxifene does not help with menopause symptoms and its antiresorptive effects are weaker than a full dose estrogen.