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The paradox of testosterone and ADT
Prostate Cancer | Last Active: Apr 26 11:59am | Replies (92)Comment receiving replies
So many people go from surgery to recurrence, It may happen in a few months or many years, but it almost every single case ADT will bring the cancer down to undetectable. We’re talking somebody that has had no cancer drugs for 17 years, His reoccurrence has occurred by having lots of testosterone right there, So taking the testosterone away, should stop the cancer.
I don’t know what you’re talking about when you say grow in a naturally low testosterone environment. The only way you get a low testosterone environment is you take a drug that cuts down the testosterone or you get an orichotomy. If the PSA rises with an ADT Drugs, then you have castrate resistance.
How is ADT counter productive If you become castrate resistant. I know in my case Lupron still kept my PSA low, After I became castrate resistant, So it did make sense to continue using it.
Maybe I have missed your point?
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My testosterone levels were below minimum threshold for a few years before the cancer was detected. Given the scarcity of testosterone, it still managed to establish and grow itself. I am assuming it had to find other sources of nourishment, or the tumor made its own testosterone. That explains its high PSA count as well as cribriform cells. Cutting off testosterone would, arguably, make the tumor more aggressive. No?