I have pondered the same question as to why not start the Biologics first without the prednisone. I see some people even have difficulty weaning off the biologics. Regarding pain levels. I am in agreement with many that it is an individual assessment. Eight months of prednisone therapy was enough! When I tapered to 2 mg my PMR pain returned. I stayed there for awhile and then made the decision to stop the prednisone. That being said, I still have polymyalgia pain that comes and goes. It is minimal and easily controlled with over-the-counter ibuprofen or Aleve. Once I got through the change of seasons with Spring I seem to be doing better. The winter cold increased my pain level. I’m looking forward to warmer sunny days soon. Wishing you well on your journey.