Hi Emerson

I also had FLOT, 3 rounds- then a break (to get married!) Then Ivor surgery.
I'm now doing another 4 rounds FLOT, then radiotherapy.
The impact of chemotherapy varies person to person, and there are definitely things you can ask for which help.
My nausea was bad for the first 2 sessions, then a friend told me about Aprepitant. This was a total game changer! I'm not sure what country/meds avail for your husband, but this one has drastically reduced nausea.
FLOT can give pins needles, this happens when you get cold or hot, it's a nerve ending thing. If you wrap warm outside, don't eat ice 7 days after chemo, and use oven mit to get stuff from freezer it helps.
My FlOT seriously reduced my tumour, and enabled me to eat-and even get married in the gap between chemo and surgery! It's definitely worth it because it kills and reduces the cancer cells. This seems to be standard one for oesophageal cancer.
Ask for any advice sheets, I found this helped me prepare.
They were able to remove my whole tumour, but I'm doing more FLOT as preventative measure. They have been able to slightly reduce levels as its 2nd lot, which lessens pins needles.
Chemo can also give a bit of dry mouth, but ask nurses for special Toothpaste/Mouthwash. Can also gargle with salt, bicarb soda and water.
I couldn't drink the nutritional drinks during chemo as made me feel sick. But took soups instead and juices.
You will find what works for him. Happy to share anything else if want to contact individually.
Best of luck 😀
Leila