Even with a low Gleason score, having a high number of positive cores and an elevated PSA puts you in a gray zone where “low risk” doesn’t feel so low. While the numbers suggest a less aggressive cancer, the sheer volume raises red flags that deserve a closer look. This is where second opinions, imaging, and possibly genomic testing can help cut through the uncertainty. You're not just a set of stats — you're the one who has to live with the decision, so make sure it's built on as much clarity as science (and a little gut instinct) can give.