← Return to Usefulness of Vitamin D supplements for bone health

Discussion

Usefulness of Vitamin D supplements for bone health

Osteoporosis & Bone Health | Last Active: 2 hours ago | Replies (25)
Comment receiving replies
@rjd

IF 30-50ng is the 'sweet spot' then why do labs report the reference number as between 30-100ng? Is there some evidence that a D3 reading above 50ng is harmful in some way, and if so, in what way is it harmful?

Jump to this post

Replies to "IF 30-50ng is the 'sweet spot' then why do labs report the reference number as between..."
njx58 | @njx58 | Apr 7 6:53pm

Sweet spot doesn't mean higher numbers are bad. I interpret it as "30-50 is sufficient for most people." People with osteoporosis can use higher amounts to help the body absorb calcium, along with taking K2 to help the calcium get to the bones.

I believe vitamin D toxicity is associated with levels 150 and higher. Too much can cause hypercalcimia, which can result in plaque in the arteries.

VIEW AND REPLY
Michael Lavacot | @michaellavacot | Apr 8 6:30pm

Hi @rjd - Here is a link to the arguments I found for 30-50ng/mL https://youtu.be/xKNdqISXkFY?si=YE-MdSAuEITxGiiU&t=1017 . There is some evidence that levels above 50ng/mL increases your risk of falling and there is also some belief that elevated 25(OH)D could increase osteoclast activity increasing bone resorption. There are vitamin D receptors on the osteoclasts and while primarily they are 1,25(OH)2D receptors, they can react to 25(OH)D levels to some extent.

VIEW AND REPLY