I had 5 yearly Reclast infusions. Never had a side effect. Phew! My endo told me last year that there are only so many Reclast infusions one can have thus I was taken off Reclast and now I have Prolia shots. After reading the comments here about Prolia ( very negative) and not having any side effects…I recently spoke to my previous endo associated with a top NYC hospital. I moved, hence, the new endo. My old endo stated that there is fantastic research on Prolia to show that it rebuilds bones and I will be on it for the rest of my life. So…I am here to say to all the naysayers….if your doctor recommends Prolia…take it!! I am 75, never had any fractures and looking forward to my next DEXA with the hopes of seeing positive bone health. Good luck to all.