Osteoporosis quite severe if I started hrt now will it help . I am 74

I had a second thought on this @tiny28
Do you have an Echolight REMS test available near you? From what I’ve read this is a much better predictor of fracture than Dexa. Seems it also looks at bone quality, not just density. Perhaps you will get a better idea of the seriousness of your bone loss and be better equipped to make decision on meds.

Hello , I have just had a video with HRT clinic in London and am going to give it a try with added testosterone as per their suggestion . It will definitely help so I hope it suits me . Will give it three months . Meanwhile I do have a healthy diet and take supplements including calcium and d vit. Fingers crossed I don’t get fracture before it works . Let’s see

Quite bad but going to give HRT and testosterone a try after a consultation today . Fingers crossed

Good luck, keep us posted if you can

Yes I do have a rems near me . Had one about 15 months ago but didn’t keep the results 🥺. I can book another soon. Will
Keep you updated on my HRT project . Meds come tommorow. Bioidentical gel and progesterone. God only knows how my body will react to it all but will try and persevere fur couple of months at least . They follow me up in three months . I am a person who tries very hard and have looked after myself all my life healthwise so I feel desperate for something to help this awful bone disease . Inside I still feel 40 but my bones tell me different . I suffer chronic fatigue also . There are some great audiobooks I listen to . It’s also a good way to switch off .

Hi @tiny28 I read that for post menopausal women, HRT could help slow bone loss rather than actively "build" bones. Some clinical studies in the past had showed that on average, a bmd increase of 2-5% is typical over a period of 1-2 years with lumbar spine seen the most gains. I didnt come across fracture reduction data or long term study results. The gain in bmd can vary depending on type of HRT, dosage, duration of therapy, age at the start of therapy and individual health profile.

I started HRT at 61, 11 years past menopause as a follow-up after Forteo therapy. My bone markers showed bone resorption (or bone breakdown) was dramatically reduced after 3-6mo on HRT and bone formation marker followed the same fate.

@mayblin
Glad to hear resorption did not increase. It makes sense that bone formation fell after going off Forteo.
I guess you’ll have to see how things progress. Hopefully HRT will keep things stable.
Fingers crossed for all of us

I actually am a physician, and I had a fragility fracture in my spine last January. It was at L1. It came out of the blue, as I have absolutely no risk factors, other than being fair and slender. My T-score was -3.1.

My endocrinologist put me on Tymlos injections (similar to Forteo, both are parathyroid hormone analogs). I've been on those for about 7 months. No real side effects.
I just had a follow-up DEXA 2 days ago, and my T-Score is now -2.1, putting me into osteopenia instead of osteoporosis. I gained a whole point!

I am also in the process of getting a dental implant. The oral surgeon looked up Tymlos online, and declared that it would be OK to proceed with it.

So, for me the therapy has been a smashing success. I have over a year more of it to complete. I'm also lifting weights, have a Power Plate vibration machine, and various supplements.
One caveat: I personally believe that my issue was caused from having Covid four times, and that is why it is correcting so rapidly. I don't think there was an underlying metabolic process.

Replying to my post because I forgot to add that I also went right back on HRT (estradiol patch and micronized progesterone) with the approval of my older male ObGYN. Estrogen is CRUCIAL for bone health. It might not be right for everyone, but it should be discussed with your caregiver. My skin and hair are nicer, I feel more cheerful, and sex is way better. I am 69.

Hi @bboon44 I'm sorry to hear your fracture, hope you've recovered well.

It's really nice to hear a great dxa improvement from only 7mo Tymlos' therapy! May I ask did you use HRT with Tymlos during the 7mo, or was HRT a fairly recent addition? Have you monitored your bone markers? Thank you.