I have definitely noticed a connection and the log I keep confirms this. Even good stress (my son's wedding) was a set back as far as my PMR. Now that I know this, I have approached life differently, telling myself that putting PMR behind me needs to be my focus for the next year. So I've scaled back all expectations for myself like big travel, social life, deadlines and projects. I've noticed a bit change that is a positive loop, like better sleep, easier to stay on a healthy diet, etc. At least for me this has been a good experience and life lesson.