Hi @boniyabes ,

My radiation oncologist recommended the 18 months of Orgovyx, in line with the NCCN treatment guidelines for high risk localized prostate cancer (12 - 36 months of ADT as of Dec. 1, 2024 guidelines revision). He did say I could stop the Orgovyx at any time if I could not tolerate it. So far, despite side effects, I am tolerating the Orgovyx quite well and plan to continue it for my remaining 12 months of the 18 months total advised.

My doctor offered the low dose (5 mg daily) of Cialis (aka Tadalafil) when I told him about the total ED and zero libido which began only a couple of weeks into the Orgovyx treatment. I wanted to try to keep the blood flowing to my penis to help prevent atrophy and shrinkage and using the Cialis made a noticeable difference. I didn't have any spontaneous erections until about 5 months into the Orgovyx, but now notice occasional nighttime erections and often wake in the morning with an erection, as was the case for me before I started the Orgovyx. My libido has improved as well. Using Cialis in conjunction with ADT is quite common for my particular situation according to my research, but it should definitely be discussed with your doctor first to see if it is appropriate for your individual situation.

Hope this info helps you!