What are your issues ? Iam only taking it because i am trying to stop bleeding after a steroid shot .. i would not like to take it at all but my gynecologist said she would like to see the uterus lining to be at 4 centimeters and mine was at 6 ,what ever that means ? She wants me to take the pearl estrogen for two weeks straight then down to to 1 pellet twice a week . It still burns and itches so it would nice not to take it at all .. thanks for your reply any info does help . 😊