No and I have had many issues with all types of meds. I only had one problem with tymlos which resolved early on. I have taken it for 15 months now. I am recovering from T-12 through S-1 inclusive fractures all at one time. I was skeptical too, but diagnosis was serious and really had no choice. I never titrated med.

cm, welcome to Connect.
The lowest I've heard of is two click, but I think you are wise. You might go up to two tomorrow. Just go slow enough that you know exactly what your reaction will be.
Tymlos is a terrific medication, but not for everyone, almost everyone, though. I hope you have luck. Let us know. Are you doing bone markers?

Hi and I am new also to this but have had great help from others on this site. I tried first dose at 8 clicks and just couldn’t handle the side effects of headache,lightheadedness and insomnia. So went 4 clicks next night and no headache but still other side effects. After reading suggestions on here, I decided to not take any until effects wore off which was almost four days and switched to two clicks and doing it in mornings. So far, I’m good and going to three clicks today after four days of two. I’m taking it slow for I’m also on other medicine getting over my fractures and Kyphoplasty and I’m just not tolerant to meds. My doctor wasn’t aware of the clicks but I am doing what I feel is best for me in being able to stay on this for many have had such great results.