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← Return to P1NP number on Tymlos
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Osteoporosis & Bone Health | Last Active: Jul 11 7:50am | Replies (22)
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I am confused,
"Before you get a lab for ionized calcium (the active form) done, you could get an estimation using this formula, according to medscape:
corrected calcium mg/dL = measured total serum calcium (mg/dL) + 0.8x(4 - Patient's albumin g/dL)
According to Tymlos' prescribing information, hypercalcemia is defined as albumin-corrected serum calcium equals or greater than 10.7mg/dL at 4 hours following injection at any visit."
If her serum Ca level is already greater than 10.7 (11.2 to be exact), ADDING an albumin correction is only going to make it worse.
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If someone's serum albumin is greater than 4g/dL, the part "0.8x(4 - patient's albumin)" will be negative and this number will be deducted from measured total serum calcium, hence resulting a lower "corrected" calcium in mg/dL. For example, if patient's serum albumin is 5g/dL, then corrected calcium will be 11.2 + 0.8x( 4-5) = 10.4 (mg/dL)