OK, my turn to “sigh”… I KNOW that both of these drugs improve metabolic pathways and their benefit is NOT simply in lowering glucose; more importantly, they prevent hyperinsulinemia, which is a direct reaction to elevated glucose levels. That’s a whole metabolic cascade way above my pay grade.
If you look back on the very first post in this thread, @jeffmarc cited the STAMPEDE trial which showed improved metabolism for a variety of levels, including lipids. So it was never just about lowering glucose.
But you cannot imagine the many, many debates about glucose that have appeared on this forum in the past year or so - way before you joined. This recurrent excess glucose/sugar causing cancer topic has been championed/debunked by just about everyone on here…it’s almost scary how much false information is still being dispatched online.
So I include the tragic passing of my friend’s son to illustrate that no amount of glucose deprivation, no metformin, no Ozempic are gonna do diddly squat if you have an aggressively deadly cancer.
All these little tidbits may be “promising” or “exciting” but when you have the “really bad cancer” as my grandmother used to say, your chances of survival are less than 10%.