I’m not the person to answer you about holding gains after stopping Reclast, sorry. But I’m interested in the same info. I’ve done 2 Reclast injections, heading for the third in a couple of months. I’ve only had the 2-3 day type side effects, though.
I see the endocrinologist next month, I’ll ask about how long Reclast should affect bone after stopping as that’s where I’ll now find myself. Originally I was so caught up in breast cancer treatment questions that Reclast was just another drug that I took. Preventing compression fractures is my number one concern as I age.
Here’s a recent study, seems like good data about Reclast, but one of the 5 authors does have a connection to Novartis. This study shows that when talking bone strength there is a difference between simply improving density and preventing fractures.
“We found that a single dose of 5 mg zoledronate prevented bone loss for 9 to 10 years in the axial skeleton and reduced the level of a bone resorption marker by at least 25% for 8 years.”
But that is about preserving bone density. Preventing fractures is something else. From the same study . . .
“Current analyses suggest that a single 5 mg dose of zoledronate and 5-yearly doses of 2.5 mg zoledronate would reduce the incidence of each fracture type over 10 years.”
Side effects from Reclast do seem to be dose dependent. Hopefully a lower dose might be easier on your body.
https://onlinelibrary.wiley.com/doi/full/10.1002/jbmr.4453
I would very much appreciate hearing back about what your endocrinologist says about the reclast. Although, if you are taking reclast preventatively because of the cancer treatment rather than because you have osteoporosis now, the answer could be different.
And I'm so sorry about your breast cancer. You definitely had bigger fish to fry than worrying about researching Reclast at the time!
I was hoping to do an anabolic plus reclast as the anabolic actually grows new, healthy bone rather than the recycled old bone of the reclast. BUT the only anabolic I can afford at the moment is Evenity, and that is the one I am least interested in taking. So who knows, I might end up on only reclast. Right now, vertigo has taken starting anything off the table anyhow.
I have to say, I find this all confusing though. If reclast stays in the body working that long, then why did my endo say I can only expect to hold onto gains from an anabolic plus reclast for 1-5 years?
I asked my endo a lot of questions that seemed totally confused by. I'm wondering if I need to switch to someone with more experience.