Damage from Iovera Nerve block prior to TKR

Posted by kathi65 @kathi65, Nov 8, 2022

I had right TKR 18 weeks ago. Prior to surgery I had lower leg neuropathy and a neurologist could not determine why after testing (you're part of the 20% of the population that gets it for an unknown reason she said). My surgeon recommended the Iovera nerve block prior to surgery because it would help with pain after the surgery. He said that the nerve block would last for about 3 months. I had no problem when the injection was done, minimal bruising and my leg was numb. It's now been more than 3 months later and I still have numbness going all the way down the inside of my thigh to my knee and when I touched the skin it feels like someone's taking a razor blade and slicing my skin open. I'm also having problems when I bend my leg in certain ways or touch my leg in certain spots I start get sharp nerve pains down on my lower leg. I don't know if this is from the Iovera injection or not. And I have a feeling nobody's really going to tell me. Has this happened to anybody else? I already had a chronic pain condition before surgery and if I had known that I would feel the way I do now I don't think I would have had my knee replaced!

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Oh Well, I had it done last June 28 and the PA that did my knee hit the nerves and I still have horrible horrible pain and the area is still hard as a rock

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I feel the same as you do. I did physical therapy 4 times, a year and a half later, they say knee is working, but still have pain and stiffness.

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@mmorey52

Yes!! I have boat boat in my right knee. It was recommended. I have IOVERA procedure because I cannot have surgery currently. The IOVER a procedure itself was not painful however, since I had it I have had paid from my day to my mid thigh. It feels like lightning is striking the area. It is dub, similar to lidocaine. However, it does not wear off. It is a constant it has not improved by D paid for boat on boat. It has just increased nerve paid that I did not have before. The doctors are not giving me any clear cut answers. They act as if it didn’t even happen. You are not alone.

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Been to physical therapy 4 times, but still pain and stiffness.
How are you doing?

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@kobesnowy

Oh Well, I had it done last June 28 and the PA that did my knee hit the nerves and I still have horrible horrible pain and the area is still hard as a rock

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So sorry, what do they say may help?

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He told me
I but your nerves
You need to either let me do it over or suffer three months
I told him I wouldn’t let him touch me from one mile away

It’s now been almost ten months and the pain is as bad still

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@kobesnowy

He told me
I but your nerves
You need to either let me do it over or suffer three months
I told him I wouldn’t let him touch me from one mile away

It’s now been almost ten months and the pain is as bad still

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Kobesnowy, how many injections with the Iovera did you have? The surgeon who 'might' do the Iovera IF I have a TKR does only the 'deep genicular' nerves. On the Iovera website, it says that the 'peripheral' nerves are also done, but this surgeon doesn't do that. I only ask because I wonder what the difference is...

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@catheem

Kobesnowy, how many injections with the Iovera did you have? The surgeon who 'might' do the Iovera IF I have a TKR does only the 'deep genicular' nerves. On the Iovera website, it says that the 'peripheral' nerves are also done, but this surgeon doesn't do that. I only ask because I wonder what the difference is...

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I honestly do not know
But this is above the knee
And near IT bands

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@satch7

I'm 20 months post Iovera and TKR. Had a normal recovery with just the kneecap numbness until 2 months ago when I experienced the same vice like pain at the knee that shot down the outside of my lower leg into my foot. Horrible pain and locked up leg for 15 min or so, then it slowly subsides. It happens regularly now. Dr says most likely a nerve issue. I'm getting an MRI today. You seem to be the only one here with a very similar experience so not sure if this Iovera related or not.

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Oh man so sorry to hear this. Please let me know what your doc says. Do you doctor at Mayo?

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@wendewithane

I opted to have the Iovera treatment prior to my total knee replacement because I have an allergy to all opiates. It sounded like the perfect procedure to help me manage the pain. Instead, I had a severe reaction. The pain was unmanageable wherein i contacted the anesthesiologist and surgeon prior to my surgery which was scheduled the following Monday morning expressing my concerns about continuing on with the surgery. I don’t think they understood the extent of the pain I was experiencing and convinced me to continue with the surgery after providing a sedative. It’s been a year and The pain is still there along with a visible scar and obvious scar tissues and bumps from the injection site. I’ve been told I’m the only person that’s ever had an allergic reaction And there’s nothing they can do to help me. I wish I never had that treatment.

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Wow.. when we went back after a week to get the knee replacement done our surgeon said the same thing as my husband could hardly walk into the hospital he was in so much pain from the Iovera. Doc assured us it will get better...well we should not have ever listened to the surgeon and listened to our own guts telling us do not do the surgery. He also had scar tissue around where the PA put in the Iovera shot and with lots and lots of physical therapy sessions the scar tissue is gone but there are still scars from where the iovera shots were placed in the skin above the knee....We went back time and time again and the surgeon did not believe us for the pain so we chose to go elsewhere for second and third opinions which they both said he had nerve damage from the iovera shot.

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I had a left TKR in 2017. It was painful, but I got through it. Additionally, and prior to that, I have had chronic peripheral neuropathy in both feet with varying degrees of pain which comes and goes, often in shooting electric like shocks. A few years after the TKR, I began experiencing pain on the inside of the knee when pressing on the bone. My surgeon suggested, more than once, that it was likely bursitis, something they have seen occasionally following TKR. I went with that, just dealing with the moderate pain. When the surgeon's clinic sent an email announcing the Iovera procedure, I contacted them, had a meeting to discuss it, and had the procedure in mid December 2024. There was more pain involved from the seven numbing injections than expected, but that was OK considering the expected outcome. On the second day following, I began experiencing extreme pain around the knee cap. Along with numbness, pins and needles along with what I relate to shingles pain when touching the thigh above the knee cap, became almost intolerable for several days. When meeting with the surgeon who performed the Iovera, he had no answers, and in fact, referred me to the chief knee surgeon in the same office. I saw him about two weeks later. He, too, had no answers and, like the first doctor, pretty much made efforts to change the subject. He recommended gabapentin and a blood test for inflammation. The gabapentin, which I had taken before for the neuropathy, just gave me diarrhea and caused me to feel stupid, while not providing any pain relief. All the while, the 3 month window when the effects of the Iovera treatment were to wear off was anticipated. That has now come and gone. Pain, however, still exists. It is less than I would rate as 10 during the days immediately following, but I would still give it a score of 7 or 8. It's continuous. The Iovera treatment is clearly the cause of an entirely new pain nightmare which is greater than any knee pain I experienced prior to the 2017 TKR. I regret for having jumped on the Iovera bandwagon and would suggest to anyone with other nerve issues, such as my neuropathy, to proceed with it only after serious consideration.

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