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Prolia side effects-increased RA inflammation

Posted by donna33 @donna33, May 19, 2023

I received my first Prolia injection in February, 2023, and since then I have had increased inflammation. I have had Rheumatoid Arthritis for 38 years and I my most recent flare up has lasted for the past 6 years. But after this injection, my inflammation has been more extreme. I also have had intense muscle and bone pain in my legs when I try to take daily walks outside as I always have. I have to stop and take breaks frequently and this has never happened to me before.
But I am most concerned about the increased RA inflammation.
Has anyone with RA experienced this?

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victor5211 | @victor5211 | Apr 3 10:07pm

Thank you Nj for letting me know. Perhaps we can keep in touch???

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katdreyer | @katdreyer | Sep 17 3:37pm

Took shot in June . Same. 40 yrs with ra. Leg pain off the chart. Some days hurts to move. No more for me !

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katdreyer | @katdreyer | Sep 17 4:24pm
In reply to @donna33 "After my first injection if Prolia, I started having severe leg pain when walking outside, and..." + (show)
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After my first injection if Prolia, I started having severe leg pain when walking outside, and had to stop every 5-10 minutes because the pain was so bad. The pain has gotten much better now, since the drug must be wearing off, but I am due for another injection and feel pressured by my MD to take another one. However, two pharmacists I know very well, have warned me that the bad leg pain is a red flag. Has anyone experienced this with Prolia? I am terrified the leg pain will start again.

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Ditto. Leg pan HORRIBLE. Took in June and had within a month. It’s now September still having it I thought it was crazy now I know I’m not. No more.

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