I would also love to see research on taking AIs or not. Having been through diagnosis, lumpectomy, stage one a, 7MM, single foci, ER positive PR positive HER2 negative, I made the personal decision to have radiation only. I am 68 and I'm choosing quality of life over the apparent small decrease AIs will provide to recurrence risk. My genetic risk factor is extremely low as well. It's a risk but one I am willing to take. I would not make this decision if I was not so early stage with all the right indicators of low risk of recurrence. It's such a tough decision.