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ADT. Afraid of it

Prostate Cancer | Last Active: 1 day ago | Replies (67)

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@northoftheborder

@retireddoc 's link was for Groups 1-3 prostate cancer:

Group 1 = Gleason 6 (3+3)
Group 2 = Gleason 7 (3+4)
Group 3 = Gleason 7 (4+3)

These patients all had radical prostatectomies, and (again, according to the summary posted by retireddoc) there was no statistically-significant difference in biochemical recurrence between the cohorts who did and didn't receive TRT later.

I don't see anything there that would apply to those of us with advanced/metastatic prostate cancer (who would usually be G8 or G9, according to my oncologist, if they even bothered to grade it); presumably the study was just about early-stage cases where the cancer was hopefully eliminated with the prostatectomy. But if additional studies confirm it, it's good news that testosterone treatment might not increase the post-surgery risk for those people.

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Replies to "@retireddoc 's link was for Groups 1-3 prostate cancer: Group 1 = Gleason 6 (3+3) Group..."

Hey North, I was 4+3 Unfavorable and even I would be VERY cautious about TRT after salvage radiation; I still believe that every case is different and being a pessimist, I would probably be the outlier that gets an especially aggressive form of PCa. I’m gonna lay low for now….
Phil