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ADT. Afraid of it

Prostate Cancer | Last Active: 19 hours ago | Replies (67)

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@heavyphil

That’s a mind blowing study, doc…turns everything on its ear. One point though - did the paper mention the Gleason scores of the 5200 men?
I mean, if they were all 3+3’s and small tumor 3+4’s with low Deciphers, I could really get behind it.
But then there’s you and your aggressive case- now on TRT!!
It seems that the triplet therapy you endured really worked for you in not only beating down the cancer but possibly “curing” (we don’t use that word!) it?
Very happy for you!
Phil

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Replies to "That’s a mind blowing study, doc…turns everything on its ear. One point though - did the..."

@retireddoc 's link was for Groups 1-3 prostate cancer:

Group 1 = Gleason 6 (3+3)
Group 2 = Gleason 7 (3+4)
Group 3 = Gleason 7 (4+3)

These patients all had radical prostatectomies, and (again, according to the summary posted by retireddoc) there was no statistically-significant difference in biochemical recurrence between the cohorts who did and didn't receive TRT later.

I don't see anything there that would apply to those of us with advanced/metastatic prostate cancer (who would usually be G8 or G9, according to my oncologist, if they even bothered to grade it); presumably the study was just about early-stage cases where the cancer was hopefully eliminated with the prostatectomy. But if additional studies confirm it, it's good news that testosterone treatment might not increase the post-surgery risk for those people.