Is PSA rise inevitable after hormone therapy?
In 2024 I had a prostatectomy & PSA rose, am a Gleason 9, stage 4. PSMA detected lung nodules (only area) that disappeared after Eligard injection and PSA became undetectable. Added Nubeqa for “doublet” therapy. Given the above, has anyone had PSA remain undetectable for a long period ? How long? Or is it inevitable PSA will rise with just doublet therapy? Is adding Chemo (Docetaxel?) INEVITABLE to keep PSA undetectable for longer? Have foot neuropathy so hesitate with chemo that risks more advanced, permanent neuropathy. So far hot flashes(big time!)only side effect from hormone therapy.
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Hot flashes a few days later but very very mild two weeks into meds..so far going well
An answer and tips if you do get hot flashes.
I had really bad hot flashes after a couple of weeks. I would wake up at night and the sheet would be soaked under me because I’ve been sweating so much. After a year, my oncologist prescribed depo-provera, Every three months, and the hot flashes became much milder and less frequent. Then I started Zytiga And the hot flashes came back, Not quite as intense.
There are other drugs that can stop hot flashes like depo-provera which I used it for four years without any problems. Other Hormones can do it.
I now wear a Wave 2 from embrlabs.com. The device has two buttons, and I have one set for hot flashes during the day and one set for all night.
Jeff I have the Wave 2 but have not noticed any relief after 2 weeks Of having the hot flashes set high for 3 minute intervals—-seems like it cools for a few seconds then ceases. Does the all night mode stay cool AND give relief? Fewer flashes? Shorter length of flashes? Exactly WHAT does it do for you?I get them every 45 minutes at night and touch the button each time but again not much relief if any—-maybe faulty gizmo? Thanks for your advice.
To set the device for the best configuration
Click the bottom left Feel button, scroll down to hot flashes and click it. Scroll down the hot flash cooler five click it, click on “hot flash cooler five” and hit start session. Click the Now round button where you hit start and it will stop the session. Now go back to the main feel screen. Hot flash cooler 5 Should be first in the list, hit the three dots in the right corner, Click on edit and make the temperature level maximum a five. Hit. Save Session. Want to repeat this for all night cool. Click the bottom left Feel button, scroll down to hot flashes and click it Pick all night cool, set The number of hours you want And start it. Then stop it and go back to the main feel screen all night cool Should be the first thing listed. Click the three dots select edit put the cooling on maximum all over to five and hit save session.
Now You have to set the buttons for what you want. To do that you go to settings/session presets. Click on “dotted button” and pick the hot flash five minute. It will probably be second in the list. Select it and hit OK.
Click blank button And select all night cool. Hit ok. DONE!
You now are configured hit the button with the raised dot two times and it will give you five minutes of cooling. Try hitting it the moment you start to feel the hot flash. It will come on a little bit and then will not get so intense.. When you’re ready to go to bed, double click the blank button and it will send cold waves. Occasionally you won’t even notice it at night, but it should stop flashes.
You can always reduce the cooling by following the above instructions.
I'm with you on the benefits of getting out on the trails and forest service roads on a mountain bike. It provides an enjoyable workout; and the time spent outdoors enjoying the forests and fields provides a much needed mental escape. We have been riding in the lowlands thus far this year. Still too much snow in the mountains, but it's starting to warm up. Keep on peddling!
Bill