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Anyone tried Kevzara for PMR?

Polymyalgia Rheumatica (PMR) | Last Active: 4 days ago | Replies (68)

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@linda7

I was on Kevzara for 8 months, until Jan. '25. I have been on prednisone for PMR for 3 1/2 years, though I also have had some GCA symptoms all along and that diagnosis has recently been added. I have no elevation of inflammation markers since I've been on prednisone. The Kevzara allowed me to feel better but only drop 1.5 mg on the prednisone, from 6.5 to 5 mg. I couldn't get below 5 and then I was cut off patient assistance from the drug company at the end of the year and could no longer afford it. I'm glad the decision was made for me because I had some worrying side effects on the Kevzara. My cholesterol and LDL went up 50 points and my rheumatologist thought I should go on a statin. That would mean adding a drug and more side effects. Also my white blood cells and neutrophils dropped below normal, indicating that my immune system was being suppressed too much and I was at risk for infections, though I have not gotten any. My rheumatologist has offered to get me on Actemra with the assumption that I also have GCA but I decided to wait and try to get my labs back to normal and see how low I can get the prednisone. Also, I would have to do some research on cost for the Actemra. I don't regret going on the Kevzara. I'm thinking the side effects will be reversible. I am open to trying the Actemra, a similar drug, but will do so with caution.

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Replies to "I was on Kevzara for 8 months, until Jan. '25. I have been on prednisone for..."

cholesterol, blood sugar, immune system, bone density, weight gain, muscle strength, eyes, gastric issues are all part of long term prednisone use. It could be the steroids.

I hope you post if you go on Actemra...I'd love to hear how it works for you!