Pancreatic Cancer: Anyone have liver metastasis after Whipple?

I had a modified Whipple in 2015 for insulinomas x 2. 3 months later had more hypoglycemia - side effect of the insulinoma. In early 2017, I had a distal pancreatectomy and splenectomy for 9 additional insulinomas. 1 month later later additional hypoglycemia that persisted. 6 years later, tumors metastasized to the liver = metastatic insulinoma. 10 years later in continue to do well on Octreotide every 28 days and other procedures to keep hypoglycemia under control. I have had great care at Mayo since 2017 to keep me well! Thankful for the care at Mayo!

Hi @rajeshaji, how did the biopsy go? Any update?

Hi I was diagnosed with stage 4 pNET in July of 2023, I had a Whipple and liver debulking on 31 October 2023. I have had monthly lanreotide injections since March of 2024 but my cancer continues to progress. A PET in November of 2024 showed that I have a tumor in my skull. At this point, I don’t know what to think anymore.

I had the Whipple October of 2024 and then 3 months later when I went in for blood test and CT scan it had went tmt liver 5 spots. Was like how could this happen being diagnosed with stage 1 thought every was going to be good. My team had given me a good out look before the Whipple. I did ask my surgeon if he could freeze the spot of cancer before he cut it out so it would be all contained. But he said that's why we do chemo before doing surgery to kill the cancer cells flowing around. I am not a Doctor but still makes sense to freeze it before cut it out so it would all stay contained. So had to go back on chemo doing Gemcitabine regiment had a CT scan 2 months later and this regiment wasn't working had a couple more spots grow. So now I am back on 5fu regiment. Hopefully I am going to get on a clinical trial soon. I see they have new trials coming out all the time. Hopefully one will work 🙏 I do feel the best that I have since this all started last year. Just hoping and praying for the best and 2 be like stage I V surviver. Have you tried to take creon for your diarrhea and stay away from foods that have fats in them. Stay positive! I wish all of you the best! Stay in touch it helps to see what others are doing and what is working because it could work for someone else also.