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DiscussionTips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)
Depression & Anxiety | Last Active: 16 hours ago | Replies (6411)Comment receiving replies
Replies to "Hello. Anybody knows if Venlafaxine XR can be dissolved in water for tapering purpose??, or is..."
You can check with your doctor to see if s/he will prescribe a different version of Venlafaxine (tablets, regular-release, different dosage strength, etc.), or give you a script that you can take to a compounding pharmacist to have tapering doses made.
In May 2019, @notaround posted that Venlafaxine XR did not dissolve in water.
My post 8/15/18: Stahl’s Essential Psychopharmacology recommends dissolving a tablet in 100 mL of juice, discarding 1 mL [you could control the taper as you wish by discarding a different amount and reducing at a different interval] and drinking the rest. After 3 days, 2 mL can be discarded, etc."—https://www.mdedge.com/psychiatry/article/103869/depression/venlafaxine-discontinuation-syndrome-prevention-and-management
In this article, different tapering methods are described and might be helpful to you (although they are specifically for benzodiazepines)—
https://www.benzoinfo.com/benzodiazepine-tapering-strategies/