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@andy1962

Hello. Anybody knows if Venlafaxine XR can be dissolved in water for tapering purpose??, or is only for the IR presentation??

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Replies to "Hello. Anybody knows if Venlafaxine XR can be dissolved in water for tapering purpose??, or is..."

You can check with your doctor to see if s/he will prescribe a different version of Venlafaxine (tablets, regular-release, different dosage strength, etc.), or give you a script that you can take to a compounding pharmacist to have tapering doses made.

In May 2019, @notaround posted that Venlafaxine XR did not dissolve in water.

My post 8/15/18: Stahl’s Essential Psychopharmacology recommends dissolving a tablet in 100 mL of juice, discarding 1 mL [you could control the taper as you wish by discarding a different amount and reducing at a different interval] and drinking the rest. After 3 days, 2 mL can be discarded, etc."—https://www.mdedge.com/psychiatry/article/103869/depression/venlafaxine-discontinuation-syndrome-prevention-and-management

In this article, different tapering methods are described and might be helpful to you (although they are specifically for benzodiazepines)—
https://www.benzoinfo.com/benzodiazepine-tapering-strategies/