My daughter has POTS. She is 48 and finally diagnosed with POTS and mast cell activation about 6 years ago. She also has Hashimoto's. She was diagnosed at Mayo Scottsdale. She has been a runner since college. When she had the table tilt test she actually passed it. The doctor said that if she quit running for a month, she would not have passed it. She does take in extra salt and wears the compression tights.