I am currently on Anastrozole ( Arimidex) but struggle with bad myalgia and depression as side effects. I don’t like to admit defeat in things so will press on but my quality of life is quite severely impacted. I feel when I reach the two years in mark I will have a rethinking discussion with my oncologist ( she is quite receptive to the quality of life issues these medications raise) as I feel suddenly ‘old’ after 11 months of treatment. It is interesting and supportive to find this forum even though I am UK based.