Ezetimide has been in the news recently. When I started rosuvastatin three years ago the benefits were minimal. After my doctor added ezetimibe as a "booster to make the statin more effective before we increase the statins" my ldl and total cholesterol (100) dropped immediately. 3 years later I learned my calcified plaque score is off the charts, however, the blessing is the calcification rather than obstruction. I fought statins for 20 years and now believe they saved my life. Ezetemibe kept my statin dosage low and I've had zero side effects.
https://www.indiatoday.in/health/story/combining-two-cholesterol-lowering-drugs-statins-ezetimibe-could-reduce-heart-attack-stroke-cases-2700425-2025-03-28