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@mspaminreno

I so relate to what you're going through. And...am sending a big hug for you and one for your wife too.
I have found that yoga nidra meditations really help me. However, when I'm going through a PEM, only rest seems to work.
I take, specifically, Astragalus and L-Carnosine which have helped with muscle strength and energy...and most recently (in the afternoons) ATP. All of which help a tiny bit during PEM...but, resting seems to be the best. (PEM is the worst...)
I'm going to try to see if resting before an event will actually allow me to participate. Fingers are crossed. My extended family invited me to Easter brunch and I'm going to see if I can do it by doing practically nothing for about 3 days before. (I get PEM from both cognitive and physical exertion).
I'm afraid to do 'progressive muscle relaxation' because it involves the use of energy when 'tensing'.
Gosh...and to think: I used to hike all over the nearby Sierra Nevada Mountains! Those days (sadly) are behind me.
My best to you and your wife.

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Replies to "I so relate to what you're going through. And...am sending a big hug for you and..."

When I have a 'big event' (family party, evening outing, etc) I do nothing the day before, really light stuff 2 days before and block out my calendar the following day. This got me to and recovered from a Rolling Stones concert & a professional hockey game!!! Both had tons of auditory & visual stimulation, along with what I now know is 'complicated' brain work-getting to an unfamiliar place, finding the right entrance, finding my seats and a bathroom. Basically , an 'event' costs 3 days-it helps me choose what is worth that.