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@savvyme1

Some people have “treatment resistant depression.” After many years of treating my depression, with many different medications, I have not found there to be any real improvement. However, when I have stopped meds, I felt worse.

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Replies to "Some people have “treatment resistant depression.” After many years of treating my depression, with many different..."

That's how I feel too; I have decades-long TRD. I never really feel better but things are a little less awful when I'm correctly medicated.