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HRT Safety

Osteoporosis & Bone Health | Last Active: 1 day ago | Replies (170)

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@newenglandtransplant

Hi, @alyssa5455 I hope you are having success with your decision making . During a recent regular checkin with my onc, she mentioned a new(ish) type of HRT and it occurred to me this may be of interest to you as well. Duavee contains both estrogen and a SERM, with the SERM eliminating the need for progesterone to protect the uterus. Like raloxifene, the SERM (bazedoxifene) has a positive effect on bone. There is a current study (PROMISE) investigating if Duavee can reduce the risk of developing invasive breast cancer after DCIS. I still have some homework to do regarding Duavee, but thought I would put it on your radar as well.

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Replies to "Hi, @alyssa5455 I hope you are having success with your decision making . During a recent..."

Hi @newenglandtransplant. Thank you for taking the time to share this information with me.
My update is that I met with another gyn who specializes in HRT and was told again that my family history of breast and other cancers made the decision to take an HRT unwise. Another factor is that the HRT would not help to build bone but only to preserve.

I think I am resigned at this point to just continue working hard with weight bearing exercise, nutrition and supplements.

I will look into Duavee and the PROMISE study in any case. I truly appreciate your thoughtfulness.