I would give you a solutions for hot flashes, but if you’re only going to be on ADT for six months, it doesn’t make any sense to do a lot about it. Have they told you that after surgery you won’t need to go back on ADT? It doesn’t seem like it from what you’re saying.

I didn’t realize I would be responding to you in more than one message track.

I took olaparib for 5 days after I stopped abiraterone, I had nightmares every night, something I have not ever had. I talked to my oncologist and said there’s no reason for me to move to olaparib yet, I should try getting on Darolutamide, And she agreed. Been on Darolutamide for 18 months and undetectable for 16 of them. First time in seven years, I’ve been undetectable for more than one month.

Going on a PARP Inhibitor concerns me, however. My red blood cell count, Hgb and hematocrit are all low, Below the minimum. I know that getting on a PARP Inhibitor is harder on those particular blood markers not sure I can tolerate it. I just hope that getting off Darolutamide will improve those particular blood counts as the PARP brings them back down

The technique you are using of going on the PARP Early avoids all the issues since you start off with normal blood counts.

This issue with the testicles getting smaller, seems to be pretty common. Even though I was on ADT for 8 years I never had that occur. Seven of those years I was on Lupron. Maybe that’s why, after eight years on ADT, my testosterone is coming back quickly. We thought it would never come back.

I’ve never had The fatigue problem with Lupron. I’ve always been pretty hyper. Maybe it slowed me down to normal. The thing is I exercise, There is a track across the street from my house and I go there twice a day and walk about a mile, Try to do it fast, I can’t run anymore. Recently, I’ve been going to the gym three times a week. Being on Lupron quickly, deteriorate your bones and your muscles. You need to exercise and do weightlifting regularly in. Surprise me about nine months ago when I found I could not get off the ground if I fell. I now can do it though I’m not the speediest guy to get up. Of course I am 77, so I need to be careful.