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@56pan

The 3 major problems I've had with Gem/Abrax. is neuropathy especially on the soles of my feet. It started on the Folfirinox but the GA has made it much worse. Like I've got 3 inches of foam rubber strapped to the bottom of my feet and causes instability. #2 is the low RBC which causes shortness of breath but daily exercise helps some with that. #3 is low WBC and I've had covid and then the flu over the last 2 1/2 months. Such a drop in my immunity. An NP that works with my oncologist has started me yesterday on Gabapentin to hopefully help with the neuropathy. Just have to see how that goes. As it is now, I walk like a duck and it's embarassing. But just thankful to the Almighty I'm still here. Thank you all for taking the time to give your input.

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Replies to "The 3 major problems I've had with Gem/Abrax. is neuropathy especially on the soles of my..."

My husband's neuropathy is horrible also. Started with toes/fingers when on folfironox, but much worse after 5 months on gem/abrax. He tried doing the ice treatment during abrax infusions. So, either that didn't work, or else the neuropathy would have been even worse without it. He tried gabapentin for a long time. Then tried doloxitine, and wasn't helping. He started using a walker about a week ago as he is so unstable when walking on numb feet/calves. Chemo has now stopped, so it will be interesting if things improve with his neuropathy. Luckily he did not get sick with his low WBC. Hope the gabapentin works for you!