Radiation and xeloda

If you do not trust your doctors, you should look for new doctors or get a second opinion. Everyone has their own journey, so it seems that dosage is not appropriate to ask. People may be able to share their side affects, but the protocol is based on your situation. I really hope for the best for you but treatment is also a mental game so if you are not confident, find your options sooner rather than later. Stay strong!

Xelota dosage seems high. Here is what Copilot (Bing Search AI) brings up:

What is typical dosage of xelota for colorectal radiation?

The typical dosage of Xeloda (capecitabine) for colorectal cancer when combined with radiation therapy is 825 mg/m² orally twice daily2. This dosage is adjusted based on individual factors like body surface area, treatment goals, and tolerance. Always consult your healthcare provider for personalized guidance.

I completed my stage 3 radiation treatment three months ago and the 825 mg/m² orally twice daily was what was prescribed for me - I'm 6' 200lbs.

You might want to question your radialogist.

I too had radiation with Xeloda, also 28 sessions. I had to take two Xeloda pills in the morning and one in the evening, but my cancer was found very early: stage 0 (positive margins on a resected polyp). The dosage depends on various factors as @gbm has mentioned. Nevertheless, if it is within your economical possibilities, do get a second opinion.

I am being confrontational and I do apologize but something has to be said here. While it is okay to google your treatment and ask questions; if you do not trust your professionals get a second opinion from professionals, not Copilot AI.

Thanks for your input. I have had 3 opinions. I think I’m just nervous and wanted to see what the norm is, but I do appreciate your understanding and grace

It appears that you have the correct dosage. However it is a simple question to ask You're oncologist for how this is determined and they can share the calculations with you. It is really important that you take the highest possible dose you can and to stay on it. If you have some adverse experiences try to push through it!

Good luck!

I had anal cancer. I was diagnosed in 2022. I was treated with Capecitabine (Xeloda) 825 mg/m for 5 days a week for 6 weeks. The Xeloda was in pill form. I also had an IV with Mitomycin 12 mg on day one of treatment. At the same time I had radiation daily for six weeks.
18 months ago, I had a colostomy. The radiation was great but destructive as well. It caused me to have fecal incontinence. My sphincter muscle was cooked and no longer functioning. The colostomy gave me back my life. Now three years out I can say that I am in remission! I don’t need any scans until next year.
I hope this helps you in some way. I just turned 75. I’m 5’3’ and weigh 154

Just for additional reference, my dosage of Xeloda during radiation was 1800 mg twice daily. I am 5"10, 176 lbs. During radiation, my main side effects seemed to be from the radiation (some fatigue, painful skin burning in the last two weeks and two weeks after last treatment and pain and spasms passing stools).

For cleanup chemo after surgery, I did four months of more intense Xeloda, 4000 mg for 14 days straight, with one week off before beginning the cycle again. I had pretty bad hand and foot syndrome from that and they eventually had to lessen the dose and cut down to 7 days on, 7 days off.

I'm sorry you're going through this. The good news is that the first few weeks of radiation are largely symptom free and the treatment does end and symptoms resolve. Your dose does seem to be about in line with what is typical. Wishing you all the best.

Thank you so much!! I start radiation and Xeloda today!