← Return to Any successful experiences with GemAbrax after awful side effects?

Discussion
Comment receiving replies
@56pan

Gives me a little hope there 199 and mark. I had 12 rounds of Folfirinox from late '23 until spring of '24 which did a very good job on my acinar cell type of pancreatic cancer. Long story and not going into it, but the short version is the Folfirinox works very well if you've got acinar cell pancreatic cancer and the BRCA 2 mutation which I had, at least it did on me. But one of the 3 small tumors on my liver was what the surgeon and oncologist called a "rogue" or "escape" lesion as the Folfirinox had no effect on it and it continued to grow. After the VA oncologist, who takes care of me now, had another DNA test done on the biopsy tissue he found out that rogue lesion had had a "reverse mutation" and the BRCA 2 mutation was gone. Told me it's rare butd it happens. Hence, he put me on Gem/Abrax which he said does a better job on cancer without the BRCA 2 mutation. I've had 8 rounds of the Gem/Abrax now and the PET scan from last week did show some shrinkage on the tumor on my pancreas and the remaining rogue guy on my liver. And the info from you two gives me some hope as I imagine I'll have to be on the Gem/Abrax for quite a while. If you don't mind, what are your ages 199 and Mark? I'm 76, which I expect will affect how long I can tolerate the Gem/Abrax.

Jump to this post


Replies to "Gives me a little hope there 199 and mark. I had 12 rounds of Folfirinox from..."

I am 75. The worst is the hair loss, fatigue and neuropathy to my feet especially. I read your description below about your neuropathy & would agree that is the same feeling. I see you are with the VA. I am trying acupuncture to relieve some of the neuropathy & if you start early enough & can continue it does help. I try using community care for the acupuncture but am not getting it half the time. Time to go to chemo..#22 this time around; total will now be 66. I have not had issues with my labs. Oh, the worst is the constipation! after chemo!