← Return to Any successful experiences with GemAbrax after awful side effects?

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@markymarkfl

I'm finishing my 26th month of GemAbrax (most of it all with Cisplatin as well.)

I had 12 rounds of Folfirinox before my Whipple.

I had 31 rounds of G+A+C after my post-Whipple recurrence, then a 4-month break for a clinical trial.

(3 rounds of lymphodepleting chemo with Cytoxan and Fludarabine during the trial).

Since the trial failed, I've had 16 rounds of G+A (6 of them also with Cisplatin).

So: 12 + 31 + 3 + 16 = 62 rounds of chemo in the last 3.5 years. The G+A has not been too bad. 🙂

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Replies to "I'm finishing my 26th month of GemAbrax (most of it all with Cisplatin as well.) I..."

Gives me a little hope there 199 and mark. I had 12 rounds of Folfirinox from late '23 until spring of '24 which did a very good job on my acinar cell type of pancreatic cancer. Long story and not going into it, but the short version is the Folfirinox works very well if you've got acinar cell pancreatic cancer and the BRCA 2 mutation which I had, at least it did on me. But one of the 3 small tumors on my liver was what the surgeon and oncologist called a "rogue" or "escape" lesion as the Folfirinox had no effect on it and it continued to grow. After the VA oncologist, who takes care of me now, had another DNA test done on the biopsy tissue he found out that rogue lesion had had a "reverse mutation" and the BRCA 2 mutation was gone. Told me it's rare butd it happens. Hence, he put me on Gem/Abrax which he said does a better job on cancer without the BRCA 2 mutation. I've had 8 rounds of the Gem/Abrax now and the PET scan from last week did show some shrinkage on the tumor on my pancreas and the remaining rogue guy on my liver. And the info from you two gives me some hope as I imagine I'll have to be on the Gem/Abrax for quite a while. If you don't mind, what are your ages 199 and Mark? I'm 76, which I expect will affect how long I can tolerate the Gem/Abrax.