Newly diagnosed and really confused: Surgery vs Chemo + Radiation

Posted by kev13168 @kev13168, Mar 9 7:37pm

Hello All, I had a tumor removed 3/4/25 and was told they felt they got it and we would monitor it closely for a period of time. They now have informed me after reading the oncology report I will need additional treatment because the tumor had moved into the second layer of my esophagus. Two treatment options are surgical or chemo and radiation for five weeks. They feel both options have a good chance. I just can’t find much information on anyone just using chemotherapy/radiation alone. Has anyone here tried this course of action?
Thank you

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@pliddle

This discussion resonates strongly with me. At 78, I am diagnosed with Stage 3 adenocarcinoma, with no apparent spreading beyond 2 layers of esophageal wall and a total blockage of my stomach necessitating a J-Tube and 17 hrs/day nutrition to maintain weight. We are fortunate to live near a comprehensive cancer treatment/research center featuring a highly experienced minimally invasive surgery program. I will start a chemo + radiation regimen in two weeks and will perhaps face the choice of surgery/no surgery others are discussing here. I am very active generally and enjoy home vegetable/fruit gardening on a fairly intensive scale. My best wishes to others who will face/have faced this decision, and especially those who report on their outcomes.

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@pliddle
Welcome to the club of esophageal cancer patients. I also had chemo and radiation which eliminated the cancer tumor without surgery. I had jtube also. I like your attitude and hope all goes well. Please let us know how it it going?
Don

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@dsh33782

@pliddle
Welcome to the club of esophageal cancer patients. I also had chemo and radiation which eliminated the cancer tumor without surgery. I had jtube also. I like your attitude and hope all goes well. Please let us know how it it going?
Don

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Thanks; I will update as things go forward. I have viewed several times a YouTube vid of a study presentation before a Thoracic Physician group where a researcher assessed patient survival data for Stage 2 and 3 Esophageal cancer patients who underwent surgery or who declined. He concluded that those opting against surgical resolution had a 20% shorter survivor time than patients who declined. He was accompanied by a Mayo Clinic senior physician who commented on the quality vs. quantity aspects of patient survival criteria. There clearly is much food for thought in this issue.

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@pliddle

Thanks; I will update as things go forward. I have viewed several times a YouTube vid of a study presentation before a Thoracic Physician group where a researcher assessed patient survival data for Stage 2 and 3 Esophageal cancer patients who underwent surgery or who declined. He concluded that those opting against surgical resolution had a 20% shorter survivor time than patients who declined. He was accompanied by a Mayo Clinic senior physician who commented on the quality vs. quantity aspects of patient survival criteria. There clearly is much food for thought in this issue.

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@pliddle
Yes, I too studied the survival statistics for esophageal cancer patients. In the end I concluded the statistics are not all that helpful. You have to do some research, ask questions, listen to doctors, make decisions, and pray that all goes well. I will be interested to hear how you get on?
Don

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Are the odds greatly improved with the surgery? My husband will be faced with this choice too, provided everything he’s currently about to do goes well. It seems like what the surgeon says he hopes as far as what he’d have to remove is a lot better than what the radiation oncologist is saying. The oncologist agrees with the surgeon. I guess the radiation guy isn’t the one doing the surgery, right? And everything is dependent upon what happens next, so my husband isn’t quite there yet.

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@dave4144

New to Mayo. My esphogectomy was in April, 2020. It had not perforated the esophageal wall but could not been nipped off by upper endoscopy. My oncologist recommended against chemo and radiation before surgery as it would weaken me somewhat. (I am now nearly 81). Also, the beginning of the pandemic informed decision making at that time. Despite a post surgery infection, I survived and treatment and am now cancer free without chemo or radiation. I get CT scans annually to confirm that fact. I hope to post a fuller reflection on the anniversary of my surgery. An esophagectomy is a radical surgery to experience. Sounds like your treatment successfully avoided it. Best wishes.

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@dave4144, welcome. It's your surgery anniversary month. I look forward to your reflection.

How are you doing now? What do you wish you had known? What thoughts do you have for anyone newly diagnosed with esophageal cancer?

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@emersonmoon

Are the odds greatly improved with the surgery? My husband will be faced with this choice too, provided everything he’s currently about to do goes well. It seems like what the surgeon says he hopes as far as what he’d have to remove is a lot better than what the radiation oncologist is saying. The oncologist agrees with the surgeon. I guess the radiation guy isn’t the one doing the surgery, right? And everything is dependent upon what happens next, so my husband isn’t quite there yet.

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Yes... surgery eligibility will be judged with the post treatment scan that shows everything has shrunk... and no distant spread. Local lymph nodes to the solid esophageal tumor are acceptable and don't necessarily make the patient stage 4. And yes... while anything we do... chemo, radiation, esophagectomy, immunotherapy... is not the cure for EC... it is doing a combination of these things that can get us to NED status. NED status is not the same as being cured either. But staying NED for 5 or more years... that is when they'll start saying we are cured. So only the passage of time (and living scan to scan) will tell us if we're cured or not. I'm in my 5th year post-op now... one scan to go in October... and they may cut me loose... no more monitoring. I'm starting to feel optimistic. And yes, of all the things we do, surgery is considered the cure (even though it is not). That's why everything else we do surrounds the surgery... first-line treatments are done in the neoadjuvant setting (before the esophagectomy)... and any treatments we do post-op are called adjuvant treatments. All of these things surround the Main Act... the esophagectomy. Post-op pathology is a big deal... where they examine everything removed during the esophagectomy under a microscope. This includes a close look at the removed esophagus as well as 15 to 40 lymph nodes. This will also dictate adjuvant treatments the patient may get. Be well.

You know how to reach me.

Gary

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@emersonmoon

Are the odds greatly improved with the surgery? My husband will be faced with this choice too, provided everything he’s currently about to do goes well. It seems like what the surgeon says he hopes as far as what he’d have to remove is a lot better than what the radiation oncologist is saying. The oncologist agrees with the surgeon. I guess the radiation guy isn’t the one doing the surgery, right? And everything is dependent upon what happens next, so my husband isn’t quite there yet.

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My surgeon told me that my best outcome would be due to having chemo, radiation and an Ivor Lewis esophogectomy. I was staged 3 locally advanced though. Anyway, you always can get a second opinion. Any responsible doctor would respect that. Good luck to you.

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